Dr. Althea PDRN Reju 5000 Cream 20g

Dr.Althea PDRN Reju 5000 Cream Product Details

Why Choose the Dr.Althea PDRN Reju 5000 Cream?

Dhaka’s heat, humidity, and pollution wear down the skin barrier fast, leaving skin dull and reactive. The Dr.Althea PDRN Reju 5000 Cream is built to repair that damage rather than sit on top of it. It supports skin renewal and helps rebuild a stressed barrier, which matters in a climate that strips moisture through AC and sweat in the same day. For tired, dull, or aging skin, that repair focus is the main draw.

The main active is PDRN (Polydeoxyribonucleotide) at 5,000ppm, the concentration behind the “5000” in the product name. PDRN sometimes comes from salmon or fish DNA, but Dr.Althea formulates this specific version as vegan, made through a fermentation process instead of a fish source. It works alongside Aureobasidium Pullulans Ferment, a probiotic-derived ingredient that fits the same biome-focused approach. Most PDRN research covers injectable use, so topical results tend to be milder than those studies suggest.

Hydration comes from a triple Hyaluronic Acid complex: Sodium Hyaluronate, Hyaluronic Acid, and Hydrolyzed Hyaluronic Acid work at different molecule sizes to hold water at multiple layers of the skin. Centella Asiatica Leaf Water makes up 5% of the formula and calms irritation while supporting barrier repair. Panthenol adds further soothing and helps skin hold onto moisture through the day.

sh-Oligopeptide-1, more commonly known as EGF (epidermal growth factor), is the ingredient behind the elasticity claims. It is a lab-made version of a protein the skin makes naturally, and some published research questions how the cosmetic form performs compared to medical-grade EGF. It remains one of the more studied cosmetic peptides, but the strongest evidence for EGF comes from injectable and medical use, not creams.

The formula skips harsh alcohols, added fragrance, and common allergens, based on brand and retailer callouts. Two ingredients marketed elsewhere for this cream, Niacinamide and Adenosine, do not appear on the printed ingredient list, so this description leaves both out rather than promise a benefit the formula may not deliver.

The cream comes in a 20g container, sized for a treatment layer rather than an everyday-only moisturizer. Dr.Althea has updated its packaging design before, so the jar or tube you receive may differ slightly from older listings without any change to the formula inside.

The Dr.Althea PDRN Reju 5000 Cream works well for dry, normal, combination, and sensitive skin dealing with dullness, fine lines, or a weak barrier. Two honest notes: very oily skin may find the rich, jelly-like texture too heavy for daytime wear, and this cream repairs and hydrates, but Niacinamide and Adenosine, the ingredients most tied to brightening and fine-line smoothing elsewhere, are not part of this formula.

Our Take: Pros and Cons of the Dr.Althea PDRN Reju 5000 Cream

Key Benefits of the Dr.Althea PDRN Reju 5000 Cream

Skin Barrier Repair Support

PDRN at 5,000ppm supports the skin’s renewal process, and Dr.Althea sources it through a vegan fermentation process rather than fish DNA. Regular use is aimed at rebuilding a stressed or damaged barrier over time.

Elasticity Support From EGF

sh-Oligopeptide-1, a lab-made version of EGF, is the ingredient behind the firmness and elasticity claims. It is one of the more researched cosmetic peptides, though the most robust evidence for EGF comes from medical, not cosmetic, studies.

Triple Hyaluronic Acid Hydration

Sodium Hyaluronate, Hyaluronic Acid, and Hydrolyzed Hyaluronic Acid hold water at different depths in the skin. Together they keep skin plump and hydrated through the day.

5% Centella Asiatica Leaf Water

Centella Asiatica Leaf Water makes up 5% of the formula and calms irritation while supporting barrier repair. Panthenol adds further soothing, easing redness and discomfort.

Lightweight, Ointment-Style Texture

The jelly-like cream absorbs without a greasy residue, sitting between a serum and a moisturizer in feel. It layers well over areas that need extra care without overloading the skin.

Fragrance-Free, Low-Irritant Formula

The cream skips added fragrance and common allergens based on brand callouts, which lowers the risk of a reaction. This makes it a reasonable pick for sensitive or reactive skin, alongside a patch test.

Star Ingredients in the Dr.Althea PDRN Reju 5000 Cream

PDRN vs Other Repair Actives in the Dr.Althea PDRN Reju 5000 Cream

The Dr.Althea PDRN Reju 5000 Cream leans on PDRN and EGF for repair and firmness rather than retinol or niacinamide, keeping the routine free of strong actives while it works on the barrier. Anyone chasing a faster, stronger anti-aging routine may still want a retinol step layered separately. For brightening specifically, a niacinamide serum works better alongside this cream than this cream alone. The vegan PDRN source is a genuine point of difference from fish-derived versions used elsewhere in the category.

Texture and Feel of the Dr.Althea PDRN Reju 5000 Cream

The Dr.Althea PDRN Reju 5000 Cream has a soft, jelly-like texture that sits between a serum and a moisturizer. A small, pea-sized amount spreads across the face and neck without pulling.

It sinks in within a minute or two and leaves a soft, slightly cushioned feel rather than a greasy film. The finish suits layering, so a thicker amount on drier patches does not feel heavy.

Dhaka’s humidity and heat can make rich creams feel like too much by midday. This jelly-cream sits lighter than a typical rich moisturizer, though very oily skin may still want a thinner layer or an application at night only.

Use it morning and night. In the morning, follow with sunscreen, since Dhaka’s UV levels stay high through most of the year.

Who Should Use the Dr.Althea PDRN Reju 5000 Cream?

• Dull, tired, or stressed skin that needs a repair-focused step

• Dry skin wanting deep, lasting hydration

• Normal skin looking for daily repair support

• Combination skin that wants balanced moisture without heaviness

• Sensitive skin dealing with occasional redness or irritation

• Anyone building a routine around PDRN or EGF actives

• Extremely oily skin may want a thinner layer or nighttime-only use

• Anyone wanting Niacinamide-level brightening should pair this with a separate serum, since this formula does not contain it

How to Use the Dr.Althea PDRN Reju 5000 Cream

Step 1: Cleanse and Prep

Wash with a gentle cleanser and apply any serum first. Let the skin settle for a moment before the cream.

Step 2: Take a Small Amount

Press out a pea-sized amount of cream. A little covers the face and neck.

Step 3: Spread and Pat

Spread it evenly across the face and neck, then tap to help it absorb. Add a thicker layer on any area that needs extra care.

Step 4: Use Morning and Night

Apply it twice a day as the last or second-to-last step in the routine. Consistent use supports the repair process.

Step 5: Follow With Sunscreen by Day

Apply sunscreen on top in the morning. Dhaka’s UV levels call for daily protection year-round.

Pro Tip for Using the Dr.Althea PDRN Reju 5000 Cream

Use this cream at night over a hydrating serum for extra repair support, since the skin does most of its renewal work while sleeping. Apply a thicker layer on any dry or irritated patches and use it as a spot treatment where needed.

Watch for packaging changes. Dr.Althea has updated the jar and tube design before, so an older or newer version arriving is normal and does not signal a different formula.

Complete Your Routine With the Dr.Althea PDRN Reju 5000 Cream

• A gentle, low-pH cleanser to start the routine

• A hydrating serum to use underneath at night

• A separate Centella-based calming ampoule for extra redness support

• A niacinamide serum for brightening, since this cream does not contain it

• A broad-spectrum sunscreen for daytime UV protection

Dr.Althea PDRN Reju 5000 Cream Full Ingredients List

Aqua (Water), Glycerin, Centella Asiatica Leaf Water, Panthenol, Butylene Glycol, Dicaprylyl Ether, 1,2-Hexanediol, Vinyl Dimethicone, Caprylyl Methicone, Hydrogenated Polydecene, Pentylene Glycol, Dicaprylyl Carbonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Olivate, Aminomethyl Propanediol, Sorbitan Olivate, Glyceryl Acrylate/Acrylic Acid Copolymer, Xanthan Gum, Ethylhexylglycerin, Sodium Hyaluronate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Phytate, Tocopherol, Aureobasidium Pullulans Ferment, Caprylic/Capric Triglyceride, Beta-Sitosterol, Hydrogenated Lecithin, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, sh-Oligopeptide-1

Glossary of Key Skincare Terms

Frequently Asked Questions About the Dr.Althea PDRN Reju 5000 Cream

What does Dr.Althea PDRN Reju 5000 Cream do for the skin?

It supports skin repair, hydration, and elasticity through PDRN, EGF, and a triple Hyaluronic Acid complex. With regular use, skin looks smoother, plumper, and less dull.

Is the PDRN in Dr.Althea PDRN Reju 5000 Cream from salmon?

No. Dr.Althea formulates the PDRN in this cream as vegan, made through a fermentation process rather than from fish or animal DNA.

Does Dr.Althea PDRN Reju 5000 Cream contain Niacinamide?

No. Niacinamide appears in some marketing descriptions for this cream, but it is not on the printed ingredient list. Pair it with a separate niacinamide serum for brightening.

Does Dr.Althea PDRN Reju 5000 Cream contain Adenosine?

No. Adenosine does not appear on the ingredient list for this cream, despite being named in some marketing copy. A dedicated adenosine or peptide serum covers that gap.

What does the “5000” mean in Dr.Althea PDRN Reju 5000 Cream?

It refers to the PDRN concentration, 5,000ppm, or about 0.5% of the formula. This is the level Dr.Althea markets as its main repair active.

Is Dr.Althea a Korean skincare brand?

Yes. Dr.Althea is a South Korean skincare brand known for pharmacy-style, repair-focused products.

Can Dr.Althea PDRN Reju 5000 Cream be used daily?

Yes. It is made for both morning and night use as part of a regular routine. Apply sunscreen on top during the day.

Is Dr.Althea PDRN Reju 5000 Cream suitable for sensitive skin?

It contains soothing ingredients like Centella Asiatica Leaf Water and Panthenol, and skips added fragrance based on brand callouts. Even so, patch testing is recommended before full use, since it does contain an EGF-type peptide.

Does Dr.Althea PDRN Reju 5000 Cream feel heavy or greasy?

No. The jelly-like texture absorbs without a greasy residue, though very oily skin may prefer a thinner layer or nighttime-only use.

What is sh-Oligopeptide-1 in Dr.Althea PDRN Reju 5000 Cream?

It is a lab-made version of EGF, or Epidermal Growth Factor, a peptide linked to skin renewal and elasticity. Cosmetic-grade EGF has some published research support, though the most robust evidence comes from medical rather than cosmetic use.

Can Dr.Althea PDRN Reju 5000 Cream be layered with other actives?

Yes. It works well with hydrating serums and calming treatments like a Centella ampoule, and layers well under sunscreen during the day.

Does Dr.Althea PDRN Reju 5000 Cream work well in Dhaka’s climate?

The lightweight, jelly-like texture holds up better than a heavy cream in Dhaka’s heat and humidity. Daily sunscreen matters just as much as the cream itself, given the strong UV levels through most of the year.